Skyrim Alchemy Profitability Calculator
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The effect Weakness to Frost (45) can be achieved in a potion if you mix these ingredients:

Abecean Longfin
Elves Ear
Fire Salts
Ice Wraith Teeth
White Cap

Here is a list of possible combinations of ingredients:

Elves Ear
Fire Salts		=>Restore Magicka
Weakness to Frost
Resist Fire		=>170
  + Taproot+ Regenerate Magicka+ 203 = 373
  + Salt Pile+ Regenerate Magicka+ 203 = 373
  + Moon Sugar+ Regenerate Magicka+ 203 = 373
  + Jazbay Grapes+ Regenerate Magicka+ 203 = 373
  + Garlic+ Regenerate Magicka+ 203 = 373
  + Dwarven Oil+ Regenerate Magicka+ 203 = 373
  + Spider Egg+ Fortify Marksman+ 134 = 304
  + Juniper Berries+ Fortify Marksman+ 134 = 304
  + Canis Root+ Fortify Marksman+ 134 = 304
 
Elves Ear
White Cap		=>Restore Magicka
Weakness to Frost		=>74
  + Spider Egg+ Fortify Marksman+ 134 = 208
  + Juniper Berries+ Fortify Marksman+ 134 = 208
  + Canis Root+ Fortify Marksman+ 134 = 208
  + Snowberries+ Resist Fire+ 96 = 170
  + Mudcrab Chitin+ Resist Fire+ 96 = 170
  + Fly Amanita+ Resist Fire+ 96 = 170
  + Fire Salts+ Resist Fire+ 96 = 170
  + Dragons Tongue+ Resist Fire+ 96 = 170
  + Bone Meal+ Resist Fire+ 96 = 170
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 134
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 134
  + Sabre Cat Tooth+ Fortify Heavy Armor+ 60 = 134
  + Ice Wraith Teeth+ Fortify Heavy Armor+ 60 = 134
  + Red Mountain Flower+ Ravage Magicka+ 16 = 90
  + Orange Dartwing+ Ravage Magicka+ 16 = 90
  + Lavender+ Ravage Magicka+ 16 = 90
  + Grass Pod+ Ravage Magicka+ 16 = 90
  + Frost Mirriam+ Ravage Magicka+ 16 = 90
 
Elves Ear
Ice Wraith Teeth		=>Weakness to Frost=>45
  + Vampire Dust+ Restore Magicka, Invisibility+ 386 = 431
  + Nirnroot+ Invisibility+ 357 = 402
  + Luna Moth Wing+ Invisibility+ 357 = 402
  + Crimson Nirnroot+ Invisibility+ 357 = 402
  + Chaurus Eggs+ Invisibility+ 357 = 402
  + Juniper Berries+ Fortify Marksman, Weakness to Fire+ 188 = 233
  + Spider Egg+ Fortify Marksman+ 134 = 179
  + Canis Root+ Fortify Marksman+ 134 = 179
  + Fire Salts+ Restore Magicka, Resist Fire+ 125 = 170
  + Snowberries+ Resist Fire+ 96 = 141
  + Mudcrab Chitin+ Resist Fire+ 96 = 141
  + Fly Amanita+ Resist Fire+ 96 = 141
  + Dragons Tongue+ Resist Fire+ 96 = 141
  + Bone Meal+ Resist Fire+ 96 = 141
  + White Cap+ Restore Magicka, Fortify Heavy Armor+ 89 = 134
  + Moon Sugar+ Restore Magicka, Weakness to Fire+ 83 = 128
  + Frost Salts+ Restore Magicka, Weakness to Fire+ 83 = 128
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 105
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 105
  + Sabre Cat Tooth+ Fortify Heavy Armor+ 60 = 105
  + Powdered Mammoth Tusk+ Weakness to Fire+ 54 = 99
  + Bleeding Crown+ Weakness to Fire+ 54 = 99
  + Taproot+ Restore Magicka+ 29 = 74
  + Red Mountain Flower+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Human Flesh+ Restore Magicka+ 29 = 74
  + Grass Pod+ Restore Magicka+ 29 = 74
  + Giant Lichen+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Dwarven Oil+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74
 
Elves Ear
Abecean Longfin		=>Weakness to Frost=>45
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Human Flesh+ Restore Magicka, Fortify Sneak+ 163 = 208
  + Spider Egg+ Fortify Marksman+ 134 = 179
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Salt Pile+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Powdered Mammoth Tusk+ Fortify Sneak+ 134 = 179
  + Juniper Berries+ Fortify Marksman+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Frost Mirriam+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Canis Root+ Fortify Marksman+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Fire Salts+ Restore Magicka, Resist Fire+ 125 = 170
  + Snowberries+ Resist Fire+ 96 = 141
  + Mudcrab Chitin+ Resist Fire+ 96 = 141
  + Fly Amanita+ Resist Fire+ 96 = 141
  + Dragons Tongue+ Resist Fire+ 96 = 141
  + Bone Meal+ Resist Fire+ 96 = 141
  + Giant Lichen+ Restore Magicka, Weakness to Poison+ 85 = 130
  + Sabre Cat Tooth+ Weakness to Poison+ 56 = 101
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Chaurus Eggs+ Weakness to Poison+ 56 = 101
  + Bleeding Crown+ Weakness to Poison+ 56 = 101
  + White Cap+ Restore Magicka+ 29 = 74
  + Vampire Dust+ Restore Magicka+ 29 = 74
  + Taproot+ Restore Magicka+ 29 = 74
  + Red Mountain Flower+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Moon Sugar+ Restore Magicka+ 29 = 74
  + Grass Pod+ Restore Magicka+ 29 = 74
  + Frost Salts+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Dwarven Oil+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74