Skyrim Alchemy Profitability Calculator
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The effect Fortify Two-handed (134) can be achieved in a potion if you mix these ingredients:

Dragons Tongue
Fly Amanita
Troll Fat

Here is a list of possible combinations of ingredients:

Troll Fat
Fly Amanita		=>Fortify Two-handed
Frenzy		=>261
  + Mudcrab Chitin+ Resist Poison, Resist Fire+ 230 = 491
  + Scaly Pholiota+ Regenerate Stamina+ 203 = 464
  + Mora Tapinella+ Regenerate Stamina+ 203 = 464
  + Bee+ Regenerate Stamina+ 203 = 464
  + Falmer Ear+ Resist Poison, Damage Health+ 140 = 401
  + Thistle Branch+ Resist Poison+ 134 = 395
  + Slaughterfish Egg+ Resist Poison+ 134 = 395
  + Grass Pod+ Resist Poison+ 134 = 395
  + Garlic+ Resist Poison+ 134 = 395
  + Charred Skeever Hide+ Resist Poison+ 134 = 395
  + Beehive Husk+ Resist Poison+ 134 = 395
  + Snowberries+ Resist Fire+ 96 = 357
  + Fire Salts+ Resist Fire+ 96 = 357
  + Elves Ear+ Resist Fire+ 96 = 357
  + Dragons Tongue+ Resist Fire+ 96 = 357
  + Bone Meal+ Resist Fire+ 96 = 357
  + Void Salts+ Damage Health+ 6 = 267
  + Small Antlers+ Damage Health+ 6 = 267
  + Skeever Tail+ Damage Health+ 6 = 267
  + River Betty+ Damage Health+ 6 = 267
  + Red Mountain Flower+ Damage Health+ 6 = 267
  + Nirnroot+ Damage Health+ 6 = 267
  + Nightshade+ Damage Health+ 6 = 267
  + Jarrin Root+ Damage Health+ 6 = 267
  + Imp Stool+ Damage Health+ 6 = 267
  + Human Heart+ Damage Health+ 6 = 267
  + Human Flesh+ Damage Health+ 6 = 267
  + Ectoplasm+ Damage Health+ 6 = 267
  + Deathbell+ Damage Health+ 6 = 267
  + Crimson Nirnroot+ Damage Health+ 6 = 267
 
Troll Fat
Dragons Tongue		=>Fortify Two-handed=>134
  + Falmer Ear+ Resist Poison, Frenzy, Damage Health+ 267 = 401
  + Mudcrab Chitin+ Resist Poison, Resist Fire+ 230 = 364
  + Fly Amanita+ Frenzy, Resist Fire+ 223 = 357
  + Thistle Branch+ Resist Poison+ 134 = 268
  + Slaughterfish Egg+ Resist Poison+ 134 = 268
  + Grass Pod+ Resist Poison+ 134 = 268
  + Garlic+ Resist Poison+ 134 = 268
  + Charred Skeever Hide+ Resist Poison+ 134 = 268
  + Beehive Husk+ Resist Poison+ 134 = 268
  + Human Heart+ Frenzy, Damage Health+ 133 = 267
  + Hagraven Feathers+ Frenzy+ 127 = 261
  + Blisterwort+ Frenzy+ 127 = 261
  + Taproot+ Fortify Illusion+ 107 = 241
  + Scaly Pholiota+ Fortify Illusion+ 107 = 241
  + Mora Tapinella+ Fortify Illusion+ 107 = 241
  + Dwarven Oil+ Fortify Illusion+ 107 = 241
  + Snowberries+ Resist Fire+ 96 = 230
  + Fire Salts+ Resist Fire+ 96 = 230
  + Elves Ear+ Resist Fire+ 96 = 230
  + Bone Meal+ Resist Fire+ 96 = 230
  + Tundra Cotton+ Fortify Barter+ 56 = 190
  + Hagraven Claw+ Fortify Barter+ 56 = 190
  + Butterfly Wing+ Fortify Barter+ 56 = 190
  + Void Salts+ Damage Health+ 6 = 140
  + Small Antlers+ Damage Health+ 6 = 140
  + Skeever Tail+ Damage Health+ 6 = 140
  + River Betty+ Damage Health+ 6 = 140
  + Red Mountain Flower+ Damage Health+ 6 = 140
  + Nirnroot+ Damage Health+ 6 = 140
  + Nightshade+ Damage Health+ 6 = 140
  + Jarrin Root+ Damage Health+ 6 = 140
  + Imp Stool+ Damage Health+ 6 = 140
  + Human Flesh+ Damage Health+ 6 = 140
  + Ectoplasm+ Damage Health+ 6 = 140
  + Deathbell+ Damage Health+ 6 = 140
  + Crimson Nirnroot+ Damage Health+ 6 = 140